EMS11430
Bismuth Stain Kits for Specific En Bloc Staining Kit consists of:
- 10 x 5ml Solution A (Sodium Tartrate, NaOH and Bismuth Subnitrate)
- 10 x 10ml Solution B (0.2M Triethanolamine-HCl buffer, pH 7.0)
Procedures
Staining solution:
- Mix Solution A and B together (One part of A into two parts of B) then adjust to pH 7.0 with 1N HCl.
- Aldehyde-fixed tissue blocks are rinsed in the above buffer and stained en-bloc with Bismuth for one hour at room temperature on a gentle rotary shaker. Post fixation is carried out with 1% Osmium Tetroxide in 0.05 M Sodium Cacodylate buffer, pH 7.2.
- Post-staining is not needed.
Reference
Locke & Huie, (1977). Bismuth staining for Light and Electron Microscopy. Tissue Cell 9, 347.