EMS26401
Components:
Phloxine Solution 1%
Alcian Blue 0.5%
Orange G Solution
Mayer's Haematoxylin
Fixation:
10% Buffered Neutral Formalin
Sections:
Cut paraffin at 6µm sections
Staining Procedures:
- Deparaffinise and hydrate slides to distilled water.
- Mayer Haematoxylin for 10 minutes. Blue in running tap water for 10 minutes. Rinse in distilled water.
- Phloxine B 1% Solution for 3 minutes. Wash in running tap water to remove excess stain. Rinse in distilled water.
- Alcian Blue, 0.5% for 5 minutes. Wash in tap water for 2 minutes. Rinse in distilled water.
- Orange G Solutionfor 13 minutes.
- Transfer to 95% alcohol, two changes, five dips each; absolute alcohol, two changes, fifteen dips each.
- Clear in Xylene and mount.
Stain Results:
Acid Mucopolysaccharides | Blue |
Prekeratin and Keratin | Orange to Red |
Nuclei | Brown |
References:
Dane, E.T., and Herman, D. L.: Stain Techn., 38:97, 1963
AFIP Manual of Histological Staining Methods, 3rd ed., Ed. L. Luna: NY, McGraw-Hill Publ., c. 1968, p.83.